Senior citizens are increasing in Bangladesh, denoted by the increased life expectancy of the population. So, it is the high time to take necessary and relevant measure for their wellbeing. In order to take any welfare measure, it is required to find out their health status particularly musculoskeletal condition. The study focuses on the musculoskeletal problems among senior ethnic citizen residing in Rangamati district. A cross-sectional comparative study was conducted. The subjects were selected conveniently and conducted among 230 senior citizens living with family or alone. A well designed semi-structured standard questionnaire was used to collect required data from the study subjects. About 80.40% subjects suffered from musculoskeletal problems and 19.60% did not have. Back pain and knee pain was prominent i.e. 35.70% and 34.60%. Neck pain, shoulder pain, elbow pain and heel pain were seen among 13%, 7.60%, 2.70% and 3.80% respondents. No statistically significant association was found between age group, gender and musculoskeletal problem.